Cellular Energy and NAD+
NAD+ is a coenzyme in hundreds of redox reactions and the substrate for sirtuins, PARPs and CD38.
Health Areas
Each health area page maps the compounds studied in that field to the delivery barriers they face and the strength of the evidence behind them. These pages describe research, not treatment: no product on this site treats, cures or prevents any disease, and every compound's regulatory status is stated on its own profile.
Energy, metabolism and aging
Cellular energy and NAD+ covers NMN, NR and NAD+ precursors and why NAD+ levels are studied in aging. Metabolic health and the incretin era covers GLP-1 and related approved medicines and what they reveal about peptide delivery. Healthy aging and longevity, mitochondrial function and body composition and the GH axis cover compounds from urolithin A and spermidine to growth hormone secretagogues, with regulatory and anti-doping status stated plainly. Each page states evidence tiers.
Protection, repair and resilience
Antioxidant defense and liver support covers glutathione, NAC and polyphenols. Tissue repair and recovery covers peptides such as BPC-157 and thymosin beta-4, where evidence is largely preclinical and sport prohibitions apply. Immune resilience and gut barrier and inflammation cover compounds studied for immune and intestinal function. Where evidence is limited to animal or cell studies, the page says so, and every prohibited compound carries its WADA status alongside the delivery discussion.
Brain, sleep and skin
Cognition and stress covers compounds including selank, semax and adaptogens. Sleep and circadian rhythm covers melatonin and its controlled-release formats. Skin, hair and collagen links our Life Sciences work to Beauty Science, including GHK-Cu, collagen peptides and NAD+ in topical formats. Several of these compounds are unapproved in most markets, and melatonin is regulated as a drug in some countries and a supplement in others, so status is stated per jurisdiction on each compound profile.
Key facts
- Statements about dietary supplements may describe structure or function but may not claim to diagnose, treat, cure or prevent disease (21 CFR 101.93)
- BPC-157, TB-500, growth hormone secretagogues and GHRH analogs are prohibited at all times in sport (WADA Prohibited List 2026, sections S0 and S2)
- Health Canada authorizes natural health product claims only when supported by evidence reviewed for the product license (Natural Health Products Regulations, SOR/2003-196)
How our delivery technology applies
Health areas matter to us because each has a characteristic delivery profile. Energy and aging compounds are mostly nucleotides and polyphenols with stability and first-pass problems. Repair and metabolic compounds are mostly peptides with protease and permeability problems. Skin actives face the stratum corneum. Grouping by area helps partners see which layer designs are relevant to their portfolio.
Tell us your health area and target market for a portfolio review.
Metabolic Health and the Incretin Era
Approved incretin medicines such as semaglutide and tirzepatide have changed metabolic medicine and shown what peptide engineering and delivery can achieve.
Healthy Aging and Longevity: A Delivery Problem First
Most longevity compounds fail at the gut wall before they reach the biology they target.
Mitochondrial Function: Getting Actives Past Two Membranes
Mitochondria sit behind the cell membrane and their own double membrane, so a compound that reaches the blood still has to reach the organelle.
Antioxidant Defense and Liver Support: Glutathione and Its Precursors
The liver's main intracellular antioxidant is glutathione, and it is hard to deliver directly.
Tissue Repair and Recovery: What Is Proven and What Is Not
Tissue repair is the health area with the widest gap between online interest and approved evidence.
Immune Resilience: Mechanisms, Status and Delivery
Immune actives range from nutrients with established roles (zinc, vitamin D) to peptides approved in some countries but not others (thymosin alpha-1) and research compounds with no approved use (LL-37).
Cognition and Stress: The Blood-Brain Barrier Is the Problem
The blood-brain barrier excludes almost all large-molecule drugs and most small ones, so cognition products are mainly a delivery challenge.
Sleep and Circadian Rhythm: Timing Is the Formulation
Sleep products fail on timing more than on dose.
Skin, Hair and Collagen: Oral and Topical Routes Together
Skin and hair actives work from two sides: topically through the stratum corneum, and orally through the blood.
Gut Barrier and Inflammation: Deliver to the Site, Not the Blood
For the gut, poor systemic absorption can be an advantage: an active that stays in the lumen and releases at the right segment acts where the barrier is.
Body Composition and the Growth Hormone Axis
The growth hormone axis has approved drugs at every level, from weekly GH to an oral diagnostic ghrelin agonist, and a larger gray market of unapproved peptides.
Related reading
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